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Clemex
Application Module · AI-Powered

Clemex Particle Size Analysis Module

Particle size is a critical quality indicator across industries, from powder metallurgy and ceramics to pharmaceuticals and advanced coatings. Yet traditional measurement methods rely on manual counting, subjective thresholding, or semi-automated tools that introduce operator variability and slow down quality workflows. Clemex's Particle Size Analysis module eliminates these bottlenecks with deep learning segmentation that detects, separates, and measures individual particles automatically, regardless of shape complexity, overlap, or contrast variations.

Stop counting particles by hand. Clemex automates what used to take hours in seconds.

Scientifically Proven Touching & Overlapping Particles Full Statistical Reporting AI-Powered Segmentation

Analysis Workflow

From Image to Result in 4 Steps

A fully automated pipeline, from raw image acquisition to a traceable, audit-ready report.

STEP 1

Acquire / Load Images

Import particle images from your microscope, camera, or existing dataset.

STEP 2

Particle Detection

Deep learning models detect and separate individual particles, including touching, overlapping, and irregular morphologies, without any manual threshold setting.

STEP 3

Size & Morphology Analysis

Particle count · D10 / D50 / D90 · Min & max diameter · Area & perimeter · Circularity · Aspect ratio · Feret diameter · Convexity.

STEP 4

Generated Report

Automatically export a fully traceable, audit-ready report in PDF or Excel, including size distributions, histograms, statistics, and standard references.

Analysis Process

Semi-Automatic

The user controls detection, adjusts segmentation, adds corrections, and verifies the analysis before finalizing the report.

Fully Automated

Detection and analysis run automatically across a batch of images with no user intervention, ideal for high-throughput quality control.

Particle Metrics

Clemex Key Particle Size Metrics & Morphological Measures

For every particle detected, Clemex computes a comprehensive set of size and shape descriptors, giving labs the full picture needed for quality control, research, and standard compliance.

Feret Diameter (Min / Max)

Caliper-based diameter measured at defined angles. Min Feret = shortest dimension; Max Feret = longest dimension. Essential for elongated and irregular particles.

Size Distribution: D10 / D50 / D90

Percentile-based distribution descriptors. D50 is the median particle size; D10 and D90 define the lower and upper spread of the population, key for standard-compliant reporting.

Area & Perimeter

Projected 2D area and boundary length of each particle, as foundational inputs for morphological shape descriptors and volume estimation.

Confidence Interval & Relative Accuracy

Statistical reliability metrics that quantify how well the measured sample represents the true population, required for standards-compliant quality reports.

Key Morphological Measures

Circularity

Ratio of particle area to the area of a perfect circle with the same perimeter. A value of 1.0 = perfect circle. Detects shape deviation in powders, cells, and droplets.

Aspect Ratio

Ratio of the major axis to minor axis. Distinguishes elongated fibers or rods from equiaxed spheres. Critical for fiber and flake classification.

Convexity

Ratio of particle perimeter to the perimeter of its convex hull. Low convexity = high surface roughness. Useful for distinguishing rough from smooth particles.

Roundness

Measures how close the particle shape is to a perfect circle based on area and max Feret diameter. Complementary to circularity, sensitive to overall bulk shape.

Solidity

Ratio of particle area to its convex hull area. Approaches 1.0 for compact particles and decreases for particles with concave indentations or branched structures.

All metrics computed per particle Min / Max Feret Area & Perimeter D10 / D50 / D90 Circularity Aspect Ratio Convexity Roundness Solidity

Key Features

Everything You Need in One Module

From acquisition to final report, Clemex covers the complete particle size analysis workflow.

AI Empowered Particle Detection

  • Separates touching and overlapping particles that confuse threshold-based methods
  • Handles spheres, irregular shapes, fibers, cells, and liquid-suspended particles in one module
AI-Powered

End-to-End Analysis Chain

Fully integrated pipeline from raw image acquisition to a traceable, audit-ready report, with no external tools, no manual exports, no broken workflows.

Fully Automated

Speed & Batch Processing

Analyze large image sets automatically at high speed (5 to 10 s/image), enabling high-throughput particle QC without operator bottlenecks.

Batch-Ready

100% Operator-Independent Repeatability

Same image, same result every time, regardless of operator, machine, or lab. Eliminates the subjectivity inherent in manual and semi-manual particle counting.

Reproducible

Hardware Flexibility

Compatible with a wide range of optical microscopes, SEM systems, and camera setups. No proprietary hardware required. Works with your existing equipment.

Hardware-Agnostic

Analysis Customization

Tailor measurement parameters, filters, size classes, and report templates to your specific materials, standards, and quality control requirements.

Customizable

Results & Reports

Clemex Particle Analysis in Action

Real analysis reports produced with Clemex Vision across pharmaceutical powders, ceramic materials, and industrial abrasives. Each card shows the detected microstructure and links to the full PDF report.

Pharmaceutical

Powder and liquid suspension analysis for drug development and QC

Ibuprofen Powder

Size and shape analysis of elongated crystals. 3,431 particles measured across 440 fields. Mean length: 87.1 µm.

Download Report ›

Paracetamol Powder

Dry and liquid-suspended particle analysis. 301 particles measured. Circular diameter range: 3.4 to 60.7 µm.

Download Report ›

Pharmaceutical Agent in Oil

Detection and separation of agglomerated particles suspended in mineral oil at 500X. Width range: 0.8 to 16.3 µm.

Download Report ›

Ceramic & Inorganic

Powder and grain detection in ceramic and inorganic materials

Ceramic Material

Particle, pore and base material detection at 200X. 18,305 particles across 12 fields. D50: 7.9 µm, D90: 24.1 µm.

Download Report ›

Ammonium Phosphate Powder

Inorganic powder size and shape characterization. Detection of fine irregular particles across a wide size range.

Download Report ›

Particle Size Distribution

General particle detection across two specimens at 50X and 200X. Full length, diameter, aspect ratio, sphericity and roughness analysis.

Download Report ›

Industrial & Abrasive

Angularity and morphology analysis for abrasive and industrial powders

Abrasive Powder Angularity

Particle angularity, roundness, length and aspect ratio at 100X. Mean angularity (Rn): 2.80. D50: 2.81 µm.

Download Report ›

Particle Morphology Library

Particle Types Analyzed by Clemex

Clemex's AI-powered particle detection engine segments and measures individual particles across a wide range of microstructures, from perfectly spherical powders to irregular rough particles, dense touching clusters, and particles suspended in liquid. Whether you work in materials science, life sciences, or industrial quality control, the module adapts to your particle morphology without manual tuning.

Bubbles

Bubble size distribution is critical in foam characterization, food science, and materials engineering where void content controls mechanical and thermal properties.

Clemex detects ring-shaped bubbles of varying contrast and size, accurately segmenting each void and delivering full size distribution statistics.

Blood Cells

Cell size and morphology are key diagnostic indicators in hematology and biomedical research, requiring precise, high-throughput measurement.

Clemex separates and measures densely packed, touching blood cells, providing count, size distribution, and morphological parameters per cell.

Fibers Cross Section

Fiber diameter and cross-sectional uniformity are critical quality parameters in composite materials, textiles, and optical fiber manufacturing.

Clemex accurately segments hundreds of tightly packed fiber cross-sections simultaneously, measuring diameter, area, and shape factor for each fiber.

Spheres

Spherical particles are common in metal additive manufacturing powders, ceramic beads, and pharmaceutical pellets where tight size control is mandatory.

Clemex delivers precise diameter, circularity, and size distribution measurements for large spherical particles, with full standard-compliant reporting.

Smooth Particles

Smooth, rounded particles appear in atomized metal powders, pigments, and polymer microspheres used in coatings and biomedical applications.

Clemex accurately segments touching and overlapping smooth particles, computing D10/D50/D90, aspect ratio, and circularity for every particle detected.

Rough Particles

Irregular, angular particles are common in crushed minerals, abrasives, and geological samples where shape characterization is as important as size.

Clemex robustly segments highly irregular morphologies, delivering Feret diameter, convexity, roundness, and full shape factor analysis alongside size metrics.

Spheres in Liquid

Particles suspended in liquid are encountered in emulsions, drug delivery systems, and colloidal suspensions where dynamic contrast and halo artifacts challenge standard methods.

Clemex handles the bright halo and low-contrast background typical of liquid-suspended particles, delivering accurate size measurement even under challenging optical conditions.

Frequently Asked Questions

What is image-based particle size analysis and how does it differ from laser diffraction?

Image-based particle size analysis uses microscopy images to directly measure individual particle dimensions, giving you actual size, shape, and morphology data for every particle detected. Laser diffraction (ISO 13320) infers size from light scattering patterns and assumes spherical geometry, making it unsuitable for elongated, irregular, or agglomerated particles. Image analysis is the only method that simultaneously delivers size and shape information, making it the preferred approach for non-spherical powders, fibers, cells, and any sample where morphology matters.

Image analysis: size and shape, not just size.

Can Clemex separate and measure touching or overlapping particles?

Yes. This is one of the most critical capabilities in real-world particle analysis. Threshold-based methods treat touching particles as a single object, drastically underestimating count and overestimating size. Clemex's deep learning segmentation model was trained specifically on touching and overlapping particle scenarios. It recognizes individual particle boundaries even in dense, clustered samples, delivering accurate per-particle measurements regardless of packing density.

No more merged particles, no more inflated sizes.

What size and shape parameters does Clemex measure for each particle?

For every detected particle, Clemex computes a comprehensive set of descriptors: Min and Max Feret diameter, area, perimeter, D10 / D50 / D90 distribution percentiles, circularity, aspect ratio, convexity, roundness, and solidity. These metrics are computed per-particle and aggregated statistically across the full population, including confidence intervals and relative accuracy, in a single automated report.

8+ metrics per particle, fully automated.

What microstructure and particle types does the module support?

Clemex's Particle Size Analysis module handles a wide spectrum of real-world microstructures in a single module, without switching models or reconfiguring settings. Supported types include: metal and ceramic powders (atomized, sintered, crushed), pharmaceutical granules and API particles, abrasives and geological materials, biological cells and blood smears, fiber cross-sections (composites, textiles), liquid-suspended particles and emulsions, and bubbles or voids in coatings and foams. Industries served include materials science, powder metallurgy, pharma & biotech, aerospace, electronics, and quality control labs.

One module, every particle type.

How does Clemex ensure repeatable and reproducible results?

Manual and semi-manual particle counting is inherently operator-dependent. Two analysts measuring the same image routinely report different results. Clemex's fully automated AI pipeline eliminates subjectivity entirely: the same image always produces the same segmentation, the same measurements, and the same report, regardless of who runs the analysis, on what machine, or in which lab. Clemex is ideal for inter-laboratory studies, audit-ready QC workflows, and regulated environments.

100% operator-independent, every time.

Does the module require manual threshold adjustment for each sample or material?

No. This is a key differentiator from conventional image analysis software. Traditional tools require the user to manually set intensity thresholds, adjust contrast, or define detection parameters for every new sample type, a slow and error-prone process. Clemex's AI model was trained on a large and diverse dataset of particle images and applies automatically to your samples from day one, with no per-material tuning required.

Zero configuration. Load images, get results.

Is the analysis compliant with image analysis standards?

Yes. Clemex's Particle Size Analysis module follows the methodology defined in static image analysis standards. Measurement parameters, statistical outputs, and report formatting are aligned with standard requirements. Every generated report includes traceable methodology and standard references, making it suitable for regulatory submissions, quality audits, and research publication.

Standards built into the pipeline.

How does Clemex handle challenging imaging conditions: low contrast, halos, or noisy backgrounds?

Real-world particle images are rarely ideal. Liquid-suspended particles create bright halos; rough surfaces produce uneven illumination; background noise mimics small particles. Clemex's deep learning model was trained on diverse, real-world conditions, not just clean lab images. It distinguishes true particles from artifacts based on morphological context, not just intensity values, enabling reliable detection even on noisy, low-contrast, or optically complex samples.

Trained on real-world images, not just ideal ones.

Can I run batch analysis across many images automatically?

Yes. Clemex supports fully automated batch processing. You define the analysis once, and the module applies it across any number of images without operator intervention. Results are aggregated across the batch and a consolidated report is generated automatically, ideal for high-throughput quality control environments, production line inspection, or large-scale research studies where hundreds of images need to be processed consistently.

From one image to thousands, same workflow.

Does Clemex work with our existing microscope and camera setup?

Clemex is fully hardware-agnostic. The Particle Size Analysis module works with any microscope or imaging system that produces standard digital image files, optical, SEM, fluorescence, or brightfield, from any manufacturer. There is no proprietary hardware requirement or vendor lock-in. If your system captures images, Clemex can analyze them.

Your hardware. Clemex intelligence.

Peer-reviewed research using Clemex particle size analysis software: View citations on Google Scholar →

Ready to Automate Your Particle Size Analysis?

Talk to a Clemex expert and get a live demo on your own sample images. No commitment required.